Abstract: A copper tailing sample from Qinghai Province contains 0.039% cobalt, reaching industrial grade. To achieve efficient recovery of this cobalt resource, 27 groups of conditional experiments were carried out using sulfation roasting leaching combined sulfation roasting-hydrochloric acid-sulfuric acid leaching processes. The effects of roasting time, roasting temperature, sulfuric acid concentration, hydrochloric acid concentration, and leaching time on cobalt leaching rates were investigated. The results show that the combined sulfation roasting combined hydrochloric acid-sulfuric acid leaching process yields the optimal performance. Under the conditions of hydrochloric acid concentration of 219 g/L, reaction temperature of 90 ℃, sulfuric acid concentration of 196 g/L, and reaction time of 2 hours, the cobalt leaching rate reaches 93.73%. This represents a 68.13% incresase compared to direct sulfuric acid leaching of unroasted tailings. Based on the tailings inventory, the expected economic value can reach approximately 1.4 billion Yuan. The utilization of tailings as a resource not only reduces environmental pollution but also generates certain economic benefits. This study provides a basis for future research on the resource utilization of tailings.