Abstract: On the basis of previous study and area soil geochemical survey in Fufeng area in the west of the Weihe Basin, data comparison of helium geochemistry, geology and geophysics and researches on Source-reservoir-cap assembly and trap conditions of helium gas in this area have been made and three helium gas accumulation anomaly areas were delineated. It is preliminarily believed that the bottled soil sampling method can effectively provide the geochemical information for the accumulation of helium resources, and can quickly delineate the favorable abnormal areas. The three anomalies identified this time have good helium accumulation conditions, which can be used as the favorable target area for further exploration of helium resources.